Duphaston: Quick Guide to Uses, Dosage & Safety

Duphaston is a brand name for dydrogesterone, a synthetic version of the hormone progesterone. It’s made to act like the natural hormone your body makes, so it can help fix hormone‑related problems without a big hormonal surge.

When Doctors Prescribe Duphaston

Doctors usually write Duphaston for irregular periods, painful periods (endometriosis), trouble getting pregnant, or a threatened miscarriage. It’s also a go‑to for hormone‑replacement therapy after menopause, especially if you need extra progesterone to balance estrogen.

How to Take Duphaston Safely

The common tablet is 10 mg. For a typical menstrual cycle you might take 10 mg twice a day for 10–14 days, starting around day 16‑20 of your cycle. If you’re using it for IVF, the schedule is often 10 mg once a day from day 2 to day 12 of the cycle. For menopause, many doctors suggest 10 mg once a day for the whole month.

Swallow the tablet whole with water. Taking it with food or on an empty stomach works fine, but keep the timing the same each day so blood levels stay steady. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one—then just skip the missed dose.

Most side effects are mild. You may feel a little nausea, a headache, breast tenderness, or mood swings. These usually fade after a week or two. Rarely, people get an allergic rash, severe dizziness, or heavy bleeding. If you notice any of those, call your doctor right away.

Duphaston can interact with some medicines. Certain antibiotics (like rifampicin), anti‑fungal drugs, and seizure meds can lower its effect. Always tell your prescriber about every medicine you’re taking, even over‑the‑counter stuff.

If you’re pregnant or planning to become pregnant, Duphaston is often safe when your doctor recommends it, but it’s not a regular prenatal vitamin. Breastfeeding moms should check with their doctor, as a tiny amount can pass into milk.

Getting Duphaston requires a prescription. Some reputable online pharmacies let you upload a valid prescription and ship the medication to your door. Make sure the pharmacy is licensed, checks your prescription, and uses secure packaging. Never buy from sites that don’t ask for a prescription or that promise “no‑prescription” sales.

Store the tablets in a cool, dry place away from direct sunlight. Keep them out of kids’ reach—accidental ingestion can be serious.

In short, Duphaston is a useful tool for many hormone‑related issues when you follow the doctor’s instructions, watch for side effects, and use a trustworthy pharmacy. Stay observant, ask questions, and you’ll get the most benefit with the least hassle.

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Sep, 25 2025

Duphaston (Dydrogesterone) vs Other Progestins: Quick Comparison Guide

A clear, side‑by‑side look at Duphaston (dydrogesterone) compared with common progesterone alternatives, covering uses, safety, cost and tips for choosing the right option.